The European Food Safety Authority (EFSA) has issued a formal safety opinion approving beta-NMN as a novel food ingredient for use in supplements at up to 300 mg/day for adults (excluding pregnant/lactating women). The Panel confirmed NMN is bioavailable as a source of niacin with a 1:1 conversion factor to nicotinamide, poses no genotoxicity concerns, and is safe based on animal and human data, with the proposed intake remaining well below the 900 mg/day upper safety limit for nicotinamide.
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EFSA confirms NMN safe up to 300 mg/day; converts 1:1 to nicotinamide, well below the 900 mg upper limit.