This early pharmacokinetic study characterized how methylene blue is absorbed, metabolized and excreted in humans and dogs following oral dosing. It is one of the original sources describing the oral absorption and disposition profile of methylene blue and is still cited for that purpose. No structured abstract is available in PubMed for this 1972 paper. This is human and animal pharmacokinetic evidence about absorption and disposition, not a study of clinical outcomes.
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Oral MB is absorbed and metabolized in both humans and dogs, informing dosing expectations in clinical use.